Mikhail Blagosklonny Says Rapamycin Could Help In the Fight against Cancer and Aging in Humans

According to Mikhail Blagosklonny, a renowned researcher, there has been a belief that the process of aging was as a result of functional deterioration that is caused by the buildup or random molecular damage. Most scientists believe that it cannot be prevented. However, Mikhail is certain that by defying this dogma could bring new hope to cancer patients. He believes that rapamycin is the answer to the treatment of cancer and the aging process. According to Mikhail, when appropriate doses of rapamycin and other rapalogs are administered efficiently, they can extend the lifespan of cancer patients.

In 2006, it was concluded that the treatment was already permitted for clinical usage and it was availed in the various stores across the world for use. In addition to being used in the cancer treatment, rapamycin can be used in the treatment of cardiovascular illnesses, autoimmunity, and metabolic disorders as well as other ailments that are linked with aging. Rapamycin has been dubbed as the finest drug for use in the fight against various types’ cancer, senescence and cell aging in humans. Mikhail notes that rapamycin is nontoxic, and can be administered every day. Follow Mikhail on Google Scholar

More information on Mikhail

Mikhail Blagosklonny studies focus on the cancer treatment and aging. Mikhail is an outstanding researcher and has an MD in internal medicine and also a Ph.D. in experimental medicine and cardiology. Mikhail Blagosklonny research focuses on cancer, explicitly targeted at cancer therapies that may help in protecting the healthy body cells from damages. Mikhail has also conducted remarkable research and taken his time to study underlying processes that lead to aging. It also involves the research of drugs that may help in stopping, or just slowing down the aging process entirely.

Mikhail Blagosklonny began serving in the New York Medical College in 2002, where he was appointed the associate professor. Mikhail then went ahead to take the role as the senior scientist at Ordway Research Institute. He continued with his tenure at the institute until 2009 when he moved to Roswell Park Cancer Institute.

Mikhail is passionate about researching on various cancer topics. He also conducts research on biogerontology, the study of aging in humans. Mikhail Blagosklonny is renowned for formulating a theory in the possible role of TOR signaling in the fight against cancer and the adverse effects of aging. He has stated that rapamycin can be used to increase the lifespan of cancer patients. Rapamycin is used in cancer therapies to slow down the multiplication of cancer cells. Besides helping to reduce the spread of cancer cells, rapamycin can also assist in boosting the immune system of cancer patients. His outstanding research in this area earned him the recognition in longevity studies as an advocate for rapamycin.

View: https://www.researchgate.net/profile/Mikhail_Blagosklonny

Mikhail has passionately supported the use of rapamycin in longevity research. Mikhail is the editor-in-chief at Aging, a monthly open access medical journal that is peer reviewed. Impact journals publish the Aging medical journal, and it mainly focuses on research on senescence gerontology and the molecular mechanisms of aging.

Roberto Santiago Is The Respected Pioneer Behind The Manaira Shopping Mall

As a young entrepreneur Brazilian born Roberto Santiago’s desire for success was obvious to those that knew and worked with him. After his first successful venture in cardboard manufacturing, in 1987 at the young age of 29, he purchased a parcel of land in his hometown of Joao Pessoa.

For the next years he worked on the development of what was then and still is today one of the most beautiful landmarks in the city of João Pessoa, the magnificent Manaira Shopping Mall that has been open since 1989. Read more on blogdogordinho.com

The now famous and unique Manaira Mall features a college, gym, retail stores, a theater, a gaming area that includes bowling, financial offices, a gymnasium and food court. In 2009 Mr Santiago introduced the Domus Hall, an entertainment venue on the mall’s roof that can hold up to 10,000 people for standing room and seat up to 4,000. The grand venue hosts concerts, weddings, ceremonies, fairs and exhibits. With a state of the art sound system, soundproofing and air conditioning, the hall draws some great Brazilian entertainers as well as top international stage names from around the world.

The food court features an eclectic variety of delicious cuisine from fast foods like burgers, pasta, Chinese carry-out, to the higher end Capital Steakhouse. Shopping options include clothing, jewelry, a book store, cosmetics, sporting goods and furniture. The mall also hosts the College Higher Education of Paraiba, whose students provide for a nice customer base.

In 2013 Roberto Santiago developed another modern mall called Mangueira, also in João Pessoa that has contributed effectively to the growth of the economy in the Brazilian city as well as created a very magnetic effect to many other companies wanting to relocate to Joao Pessoa because of the economic boost Santiago has injected into the city.

A favorite of locals and tourist alike. Conveniently located in the heart of the northeastern coast city, beautiful beaches are close buy and the draw of the magnificently designed mall, one of the Brazil’s largest shopping centers, has moved Santiago to expand the Manaira Mall five times since it’s opening in 1989, with the largest expansion coming in 2013. The shopping mall has enjoyed a healthy new customer growth rate of up to 15% year after year.

With over 92,000 square meters covering the Manaira one of the must visit areas in the shopping mall is the amazing theater that offers movie lovers 11 viewing theaters, VIP rooms and a state of the art modernized 3D rooms. Read more on comunique-se.com.

The cultural growth and economic development that Santiago has brought to his hometown over the last 20 years has made him a pioneer and leader that the community can be both proud of and grateful for.

Co-designing Investment Solutions to Fulfill Various Needs of Investors

Mr. Warren Buffet shared pieces of his seasoned experience on investing techniques and strategies on recent annual shareholder letter. He has always committed himself to simple investments at relatively lower costs. He says he settled for long-term investments that made viable returns in spite of a long time that he would wait. The investment approach, popularly referred to as bottom-up involves a thorough examination of companies and building a robust portfolio

Consumers need to be aware of labels that many businesses use for their products. Many mutual funds result in low profits due to the high cost of management and trading in an excessive manner. The manifestation of such like scenario brings about volatile risks, and unknown missed opportunities of passive investments. The tipping point of consideration should be to realize whether the investment makes a profit or loss.

Timothy Armour was born in the year 1960 and attended a private freethinking arts college called Middlebury College in Middlebury situated in the United States. The Chairman who also serves as Director and Chief Executive Officer at Capital Research, after obtaining a Bachelor’s Degree in Economics, began his career life in 1993 as a participant in a Program for Associates. Later he served as an Equity Portfolio Manager where he gained much experience in investment. Before, he worked as an asset Analyst where he pursued global communications and servicing various companies.

In the year 2015, It was declared by Capital Group’s Board of Directors concerning the election of Tim Armour as the Chairman of Capital Group.

Armour has much respect to managers working under him and who pay close concentration at the smaller detail of companies. He dislikes the act of following a course that has no guaranteed potential. Besides, he hints a broader plan that entails re-designing investment solutions which can promote saving culture, retirement, and issues related to proper insurance cover and learn more about Timothy.

Capital Group partnered with Samsung Asset Management situated in Seoul. The cooperation was meant to create development investment strategies that would guide retail investors and institutions in Korea. Tim Armour announced that the greater plan was to co-design investment solutions to fulfill various needs of Korean Investors and Timothy’s lacrosse camp.

More visit: https://en.wikipedia.org/wiki/Capital_Group_Companies

Mike Baur Is Investing In Switzerland’s Future

Mike Baur left a successful career to become a founder of Swiss Startup Factory. He has been part of the banking industry for twenty years. He understands the private banking industry is built on traditions, but he also expresses he is not a traditional person. It was time for him to explore a new venture in his life. He has an entrepreneurial spirit the desire to change the ordinary.

 

Baur explains that the reason Swiss Startup Factory includes the word “factory” is because the companies desire to produce more Swiss founded companies. They believe they manufacture companies in the way a traditional factory might produce tangible objects. He also explains that similar to a factory, the younger generation is having to work harder than ever before to produce these companies in the Swiss market.

 

The difference between the Swiss Startup Factory from other incubators is the fact that the founders and co-founders are literally paying for the opportunities with their own funds and hard work. They dedicate a great deal of time to their profession and helping others become successful and financially sustainable companies. They also aren’t involved in the politics that other companies might promote or be a part of. They are independent from others and completely fund their ventures on their own.

 

Baur sincerely believes that Switzerland is the best innovative country in the world and sees the future ecosystem flourishing, which will provide more opportunities and wealth for the citizens of Switzerland. His company is wise in knowing how to execute brilliant ideas that are developed by the youth and young start ups. The Swiss Startup Factory is also brilliant with innovating and expanding on dreams and potentials.

 

He is motivated by observing the success of others. Baur has a strong sense of community, and knows that by uniting and helping one another be successful it benefits the country as a whole. By working hard and watching the result of that hard work it motivates him to continue pushing forth each day.

 

Michael Baur gives back to the community by investing in the future of Switzerland. The ecosystem is changing rapidly and its time to be aggressive and push forward. They currently provide a 3 month long start-up accelerator program where they individually provide mentoring, coaching, office space and personalized services. They also offer financial services to assist with the beginnings of your entrepreneurial venture. They are also intertwined with a large entrepreneurial network to assist with other needs during your program to growth.

 

 

Bob Reina Is Truly Inspiring

Bob Reina is inspiring people and that is high praise, without question. He is showing people they can make a difference and they can make a change. It is up to them to go out and actually do it. It is really not that complicated when people sit down and think about it. Oftentimes, they make it harder in their heads when all they have to do is just go out there and take the first step. Bob Reina has always been ready to go out there and do what he can for society. That has never been something he is afraid of and that is something he embraces to the fullest degree.Learn more : http://inspirery.com/bob-reina/

 

With Talk Fusion, he knows he is impacting people’s lives in ways that will make them happy, satisfied, and completely fulfilled. That is something that has been missing for people for a long time. Here is the thing that a lot of people don’t realize: there are a lot of talented and creative people out there living in the world. They just have maybe been a little afraid to take a risk and put themselves out there. They are afraid to fail. There is nothing wrong with failing. In fact, many times, people learn their best lessons from failing. They learn how to get back up again and go after it and learn from what went wrong.

 

Bob Reina does not want to tell people how to live their lives. That is not up to him to decide. However, he does want people to live a life that is true to who they are at their core. He wants people to feel comfortable in their shoes and wake up every morning and like the person that is looking back at them. That comes with satisfaction and working a job that is suited for them.Learn more : http://yourmarkontheworld.com/talk-fusion-founder-ceo-bob-reinas-mission-change-lives/

 

Talk Fusion, the video communications provider, has video newsletters, video emails, video conferences, and video chats. These are what people need to get their feet off the ground and really see their business flourish. That is what makes Bob Reina happy more than anything.Learn more : http://www.superbcrew.com/talk-fusion-delivers-award-winning-video-communication-products-and-video-marketing-solutions/

 

 

Don Ressler: Top to Bottom E-Commerce Brilliance

It seems like Don Ressler doesn’t like to run or manage a company; he likes to create them, start them and then sell them. With an impressive track record of successful start-ups; he is known as someone who can can accomplish the most difficult aspect that an entrepreneur faces; getting funded.

It takes a lot of capital to get a new company up and running and then to a state of profitability.

One original company Don Ressler was part founder of is JustFab and it is still in operation as part of the TechStyle Fashion Group which is an umbrella type corporation with several subsidiaries including JustFab, FabKids, ShoeDazzle and Fabletics.

The idea on eyepain.org was some what new, ‘Subscription Based’ online stores, and the competition was fierce. Yet Don Ressler of JustFab was able to get some serious financial backing from the Matrix Partners venture capital firm despite the fact that normally invested in tech stuff like software programs, data storage, etc. Funding of $33 million in 2011 and another 76 million in 2012.

Going back a decade or so; he first started with an online company called FitnessHeaven which was bought by Intermix Media in 2001. As part of Intermix Media Don Ressler met Adam Goldenberg and the two teamed up to form a division within Intermix called Alena Media.

Alena Media was an ‘online performance advertising’ business which meant ‘Pay-for Performance’ as in you only get paid if the advertiser gets a definitive result. Risky business to some but another day at the office for Don Ressler as Alena Media was stated as being the only profitable division within Intermix Media.

In 2005 he felt his success and ideas were being dismissed before they were understood so he left Intermix Media and, again with Adam Goldenberg, formed Intelligent Beauty which led to the very successful online company JustFab.

Looking to expand the marketing outreach of JustFab; Don Ressler looked outside the box and found several companies that were running the same type of online business with similar, but slightly different markets. FabKids and Fab-Shoes were purchased by JustFab as well as ShoeDazzle. JustFab then created Fabletics, which focused on athletic wear, and all this took place in a single year; 2013.

In 2016 JustFab, FabKids, Fab-Shoes, Fabletics and ShoeDazzle were consolidated under a new parent company that is now known primarily as TechStyle. Even though the primary base of all five companies is online e-commerce; there are significant plans for expansion into the ‘Brick and Mortar’ store front world.

Read more: JustFab raises $85M at what sources say is a $1B valuation

Samuel Strauch: The Miami Real Estate Tycoon

Have you have ever heard of the amazing and talented Samuel Strauch from Florida? He is an extraordinary real estate expert and agent based in south Florida. Recently, Samuel Strauch has released a list of 10 outstanding United States cities with the nicest suburban neighborhoods. Strauch expresses how life has drastically changed for millennials who seem to be searching for affordable housing, clean streets, low crime areas and excellent schools for their children. They do not have to worry about walking their child to school or simply going to the grocery store to buy some food. Young families can now have the best when living at a steady financial income. These cities include: 1. Denver, Colorado 2. Dallas, Texas 3. San Francisco, California 4. Austin, Texas 5. Tampa, Florida 6. Orlando, Florida 7. Miami, Florida 8. San Jose, California 9. Nashville, Tennessee 10. Raleigh, North Carolina and more information click here.

Now on to Strauch, who is the main owner of Metrik Real Estate and he is involved in equity, sourcing, management, development, brokerage and acquisitions all over southern Florida with a high concentration in Miami as well as in Latin America. Strauch and his astonishing team have earned a massive and impressive reputation which goes back around 15 years. They always make sure that their customer service is top-notch when speaking to their clients. Strauch has a strong emphasis in making sure that they pick the phone with the ultimate professionalism to communicate with their clients and his Twitter.

In addition to his real estate empire, Strauch is also a wonderful investor. He invests heavily in restaurants and internet companies. He believes food is part of life and needs to be perfected so that people live and are deeply influenced by food. Strauch also believes the internet is the future as he invests in internet companies that strive to make it much simpler for people to live with the help of technology. He holds a Bachelor’s degree in International Business from the wonderful Hofstra University. Strauch was always a studious and smart student. Whenever he was confused or did not know what to do, he would always ask a question or he would get help to finish the assigned task and learn more about Samuel.

Other Reference: http://samuelstrauch.blogspot.com/

Omar Yunes Makes his Sushi Itto Winning the Best Franchisee of the World Award

Omar Yunes, an investor and entrepreneur from Mexico, won the Best Franchisee of the World or BFW competition – 2015 for his franchise of Sushi Itto. The event took place on December 5, 2015, in Florence, Italy, and that recognized the contributions of Yunes to the brand he businesses with. He has opened 13 franchise units of the Japanese food maker in Mexico, and it has outlets in Puebla, Mexico City, and Veracruz, which is roughly counting to 10% of the total units of the brand in the country. “I am excited but would like to remind that I am just a representative of the hard work put by more than 400 employees of our 13 units. I also thank the brand which provided us the space for innovation,” Yunes responded to the achievement.

The edition had participants from 34 countries around the world including Hungary, Brazil, Portugal, France, Italy, Mexico, and Argentina. Each of the franchises was evaluated by the BFW committee based on the amount of influence it creates in the network, the contributions with respect to knowledge, motivation to employees, savings implemented in the units and the system, and total improvements suggested and applied to the brand and its network. However, the brand and its value were not taken into consideration. Diego Elizarrarrás, the organizer of BFW Mexico, concluded that Omar could grab the Award because he acted as a change factor in the relationship between franchising and franchise. He also implemented control boards and better management of information to ensure efficient operation and service across the units.

Omar Yunes showed interest towards entrepreneurship from his school days and founded the first unit of Sushi Itto at the age of 21. His commitment to providing great quality food and hospitality experience has helped the franchise units to grow to 13 in a short span of time. Yunes is also finding ways to add innovation to the units and try to implement state-of-the-art technology in its operations to ensure consistent and efficient service to the customers. He is on a mission to expand the great food experience to other parts of the country.